Cover art for The a16z Show

Inside Moderna’s Personalized Cancer Vaccine

The a16z Show

Published
September 2, 2026
Duration
40:10
Summary source
description
Last updated
Sep 23, 2026

Discusses a16z General Partner Jorge Conde sits down with Moderna CEO Stéphane Bancel to discuss a major miles…

Summary

a16z General Partner Jorge Conde sits down with Moderna CEO Stéphane Bancel to discuss a major milestone for mRNA technology: positive Phase 3 results from Moderna and Merck’s individualized treatment for melanoma, after more than a decade of work on personalized cancer vaccines. Stéphane explains how the treatment works by sequencing an individual patien…

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Show notes

a16z General Partner Jorge Conde sits down with Moderna CEO Stéphane Bancel to discuss a major milestone for mRNA technology: positive Phase 3 results from Moderna and Merck’s individualized treatment for melanoma, after more than a decade of work on personalized cancer vaccines. Stéphane explains how the treatment works by sequencing an individual patient’s tumor and healthy cells, identifying the mutations most relevant to their cancer, and encoding up to 34 of them into an mRNA designed speci