Cover art for The a16z Show

David George & Jack Altman on AI, Autonomy, and the Next $25 Trillion

The a16z Show

Published
October 4, 2026
Duration
55:03
Summary source
description
Last updated
Oct 7, 2026

Discusses ai.

Summary

a16z General Partner David George joins Jack Altman on Uncapped to make the case that many of the biggest debates in AI are framed the wrong way. Frontier models or open source? Labs or applications? David’s answer is often “and.” With AI adoption still concentrated among a relatively small group of heavy users, he argues there could be room for multiple …

Intelligent Report

Sign in to read teasers, or upgrade to Research Pro to commission intelligent report for this episode. Learn more →

Show notes

a16z General Partner David George joins Jack Altman on Uncapped to make the case that many of the biggest debates in AI are framed the wrong way. Frontier models or open source? Labs or applications? David’s answer is often “and.” With AI adoption still concentrated among a relatively small group of heavy users, he argues there could be room for multiple layers of the stack to grow at once. David and Jack discuss why demand for compute continues to outstrip supply, why applications can thrive ev

Themes

  • ai
David George & Jack Altman on AI, Autonomy, and the Next $25 Trillion | The a16z Show | Vagelintel