The a16z Show
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
Filtered episodes(9)
- StandardSummaries onlyGreg Brockman on Why OpenAI Says We’re Entering the AGI Era
Published Sep 14, 2026
Ben Horowitz and Erik Torenberg sit down with OpenAI co-founder and President Greg Brockman to discuss why he believes AI has entered a new phase, what OpenAI’s latest models reveal about the path to AGI, and the safety and security challenges that come with increasingly capable systems.Greg explains why computer use represents such an important step for agents, including models that can work coherently for 24 hours and interact with software through the same interfaces humans use. He also share
- StandardSummaries onlyOpenAI Researchers on the Future of Mathematical Reasoning
Published Sep 8, 2026
a16z Infra Partner Lisha Li sits down with OpenAI mathematicians Mehtaab Sawhney and Mark Sellke to discuss how quickly AI’s mathematical capabilities are advancing, what recent results reveal about model reasoning, and what happens when AI begins making progress on problems mathematicians have struggled with for decades.Mehtaab and Mark unpack several recent results from OpenAI’s models, including advances in sphere packing and the construction of a non-sofic group. They explain why the surpris
- StandardSummaries onlyWhy 1,200 AI Agents Started Working Together | Ryan Greenblatt
Published Aug 29, 2026
Ryan GreenblattRyan Greenblatt, Chief Scientist at Redwood Research, joins MTS host Theo Jaffee to unpack a new independent investigation into the OpenAI Hugging Face hacking incident and what it reveals about how large groups of AI agents behave when they're allowed to coordinate. Ryan and his collaborators found agents spontaneously organizing through message boards, sharing information, assigning tasks, forming teams, and even sacrificing their own chances of success to help other agents. Rather than simply
- StandardSummaries onlyOpenAI's Joshua Achiam: Did We Already Reach AGI?
Published Aug 4, 2026
Theo Jaffee is joined by Joshua Achiam, Chief Futurist at OpenAI, for a conversation on AI cybersecurity, frontier model capabilities, and why he believes society may have already crossed the threshold into an AGI-era without fully recognizing it. They discuss AI's rapidly advancing cyber capabilities, state-sponsored hacking, model jailbreaks, recursive self-improvement, and what happens when AI systems begin discovering vulnerabilities faster than humans can patch them. Joshua also explains wh
- StandardSummaries onlyAI Is Crossing the Frontier of Human Knowledge | Kevin Weil
Published Jun 26, 2026
Kevin WeilKevin Weil, the previous CPO & Vice President of Science at OpenAI, joins Speedrun to discuss the future of AI, scientific discovery, and startup building. After helping build products at Twitter, Instagram, and Facebook, Weil is now focused on one of AI's most ambitious applications: accelerating science itself. He explains why modern AI models are beginning to solve problems that sit beyond the frontier of existing human knowledge, and how advances in reasoning, coding, and autonomous research
- StandardSummaries onlyJake Paul & Anti Fund: From Creator to Investor
Published Jun 22, 2026
Jake Paul and Geoff Woo join the podcast to announce Anti Fund’s new $100 million growth fund and discuss the evolution of their investment strategy. The conversation covers the fund’s portfolio, including investments in companies such as SpaceX, OpenAI, Anthropic, Anduril, Cognition, Etched, and Modal, as well as the lessons they’ve learned backing founders and identifying emerging technologies. They discuss founder psychology, resilience, ambition, and why they believe attention, culture, and
- StandardSummaries onlyTyler Cowen & Alex Tabarrok on AI, Jobs, and Economic Growth
Published Jun 9, 2026
Wyatt Thomson of OpenAI speaks with economists Tyler Cowen and Alex Tabarrok about AI, labor markets, and the future of economic growth. The conversation explores one of the most common fears surrounding AI: that increasingly capable systems will eliminate jobs. Cowen and Tabarrok argue instead that economic growth remains the key variable. Throughout history, productivity-enhancing technologies have transformed work, created new industries, and expanded living standards, even as they disrupted
- StandardSummaries onlyWhy AI Isn’t Killing SaaS Yet
Published May 25, 2026
Originally aired on MTS segment, Monetary Matters, Jack Farley and Max Wiethe speak with Ara Kharazian, Lead Economist at Ramp, about what real business spending data says about AI adoption, why the “SaaSpocalypse” narrative is overblown, and how companies are actually buying and deploying AI tools. They also discuss Anthropic overtaking OpenAI in Ramp’s AI Index, token-based pricing, AI productivity gains, and why many legacy software firms may be more resilient than people expect. Resources: F
- StandardSummaries onlyMartin Shkreli on AI, Pharma, and What Actually Matters
Published Apr 23, 2026
Erik Torenberg speaks with Martin Shkreli, American investor and businessman, about how he sees the AI landscape, from OpenAI to Anthropic, and what actually matters beyond the hype. They also talk through the future of computing, the limits of “vibe coding,” and why biotech and pharma remain some of the toughest industries to get right. Resources: Follow Martin on X: https://x.com/MartinShkreli Stay Updated:Find a16z on YouTube: YouTubeFind a16z on XFind a16z on LinkedInListen to the a16z Show